SCHEMBL29657183

SCHEMBL29657183

COP(=O)(OC)C1c2ccccc2C=C(Br)N1C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23356568 0.82 HDAC4 (0.36) HDAC4HDAC7HDAC5
SCHEMBL29657126 0.80 DRD2 (0.32)
SCHEMBL29657219 0.79 HSD11B1 (0.38) ALDH1A1TDP1
SCHEMBL29657202 0.74 BRD4 (0.44) ALDH1A1TDP1
SCHEMBL29657221 0.72 KMT2A (0.31) ALDH1A1SMN1; SMN2
SCHEMBL29657203 0.70 GPR3 (0.51) HDAC4HDAC7HDAC5ALDH1A1
SCHEMBL29657122 0.68
SCHEMBL29657247 0.66 GPR84 (0.34)
SCHEMBL29657164 0.66 GPR84 (0.34)
SCHEMBL29657243 0.64 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286240-B2 Catalyst bound alpha radical and synthesis of OXO compounds using the same COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-03-29 US claimed
US-11286240-B2 Catalyst bound alpha radical and synthesis of OXO compounds using the same COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2022-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286240-B2 Catalyst bound alpha radical and synthesis of OXO compounds using the same CBR1, POR, CAT HDAC4 4219/4885HDAC7 4412/4885HDAC5 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.