Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374494 | 0.93 | PTGS1 (0.48) | KMT2AALOX15BLMPMP22PTGS1 | |
| SCHEMBL30558179 | 0.91 | KMT2A (0.49) | KMT2AALOX15BLMPMP22PTGS1 | |
| SCHEMBL24977 | 0.88 | ECE1 (0.46) | KMT2APTGS1GSTK1NOD1ECE1 | |
| SCHEMBL29670065 | 0.87 | PTGS1 (0.48) | KMT2AALOX15BLMPMP22PTGS1 | |
| SCHEMBL29630572 | 0.87 | GLO1 (0.43) | KMT2AALOX15BLMPMP22PTGS1 | |
| SCHEMBL29630446 | 0.85 | PTGS1 (0.47) | KMT2APTGS1GSTK1DPP4DPP8 | |
| SCHEMBL29590533 | 0.85 | NOD1 (0.41) | KMT2AALOX15BLMPMP22PTGS1 | |
| SCHEMBL901330 | 0.85 | ECE1 (0.43) | KMT2APTGS1GSTK1NOD1ECE1 | |
| SCHEMBL4803053 | 0.85 | ECE1 (0.43) | KMT2APTGS1GSTK1ECE1GLO1 | |
| SCHEMBL7454476 | 0.85 | ECE1 (0.43) | KMT2APTGS1GSTK1NOD1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478789-A | anti-PD-L1 and OX40 bispecific antibodies and uses thereof | 安徽安科生物工程（集团）股份有限公司 | 2022-05-13 | — | — | CN | disclosed |