Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18548700 | 1.00 | MCL1 (0.39) | MCL1KDM4EALDH1A1SMN1; SMN2FABP4 | |
| SCHEMBL18548595 | 0.89 | ALDH1A1 (0.38) | MCL1KDM4EALDH1A1SMN1; SMN2PTPN1 | |
| SCHEMBL29660237 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18548667 | 0.80 | RAD51 (0.44) | KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29660196 | 0.79 | MGAM (0.46) | KDM4EALDH1A1SMN1; SMN2PTPN1ALOX15 | |
| SCHEMBL22309751 | 0.79 | MAPT (0.35) | MCL1ALDH1A1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL18548670 | 0.79 | MGAM (0.46) | KDM4EALDH1A1SMN1; SMN2PTPN1ALOX15 | |
| SCHEMBL22309750 | 0.75 | TP53 (0.36) | ALDH1A1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL27365442 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2PTPN1 | |
| SCHEMBL29660204 | 0.73 | GRM5 (0.42) | KDM4EALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344637-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344637-B2 | Probes for imaging huntingtin protein | HTT, HYPK, HSPBP1 | MCL1 3712/4885KDM4E 4585/4885ALDH1A1 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.