Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660409 | 0.86 | MAPT (0.46) | KDM4EALDH1A1HSD17B10TP53TRPM8 | |
| SCHEMBL29660334 | 0.83 | TARBP2 (0.44) | KDM4EALDH1A1HSD17B10TP53TRPM8 | |
| SCHEMBL29660324 | 0.80 | MAPT (0.42) | KDM4EALDH1A1HSD17B10TP53PTPN11 | |
| SCHEMBL29660317 | 0.80 | PTPN11 (0.44) | KDM4EALDH1A1HSD17B10TP53TRPM8 | |
| SCHEMBL29660332 | 0.80 | MMP13 (0.39) | KDM4EALDH1A1HSD17B10TP53PTPN11 | |
| SCHEMBL29660340 | 0.78 | MAPT (0.40) | KDM4EALDH1A1HSD17B10TP53PTPN11 | |
| SCHEMBL29660360 | 0.78 | TARBP2 (0.41) | KDM4EALDH1A1HSD17B10TP53PTPN11 | |
| SCHEMBL29911091 | 0.77 | MAPT (0.41) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL29660309 | 0.76 | MAPT (0.43) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL29660299 | 0.76 | HSD17B10 (0.40) | KDM4EALDH1A1HSD17B10TP53TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-09-15 | — | — | US | disclosed |
| EP-4003955-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | LIPC, LIPG, PNLIP | KDM4E 3614/4885ALDH1A1 2464/4885HSD17B10 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.