Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660317 | 0.86 | PTPN11 (0.44) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660409 | 0.85 | MAPT (0.46) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660340 | 0.84 | MAPT (0.40) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660360 | 0.84 | TARBP2 (0.41) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660417 | 0.82 | ALDH1A1 (0.43) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660334 | 0.82 | TARBP2 (0.44) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660299 | 0.81 | HSD17B10 (0.40) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660346 | 0.81 | MAPT (0.42) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29911091 | 0.80 | MAPT (0.41) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29660337 | 0.80 | KDM4E (0.42) | MAPTKDM4ERAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-09-15 | — | — | US | disclosed |
| EP-4003955-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | LIPC, LIPG, PNLIP | MAPT 2152/4885KDM4E 3614/4885RAB9A 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.