Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29660331 | 0.86 | PTPN11 (0.46) | ALDH1A1LMNARAB9ANPC1HSD17B10 | |
| SCHEMBL29660324 | 0.82 | MAPT (0.42) | ALDH1A1RAB9ANPC1HSD17B10MAPT | |
| SCHEMBL29660327 | 0.81 | P2RY12 (0.44) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2078743 | 0.76 | TRPM8 (0.61) | ALDH1A1LMNARAB9ANPC1HSD17B10 | |
| SCHEMBL29911121 | 0.76 | L3MBTL1 (0.57) | LMNAMAPTPTPN11KDM4ETP53 | |
| SCHEMBL29660336 | 0.76 | PTPN11 (0.55) | MAPTPTPN11KDM4ETP53RARB | |
| SCHEMBL13345947 | 0.73 | RARB (0.53) | ALDH1A1LMNARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13345951 | 0.73 | L3MBTL1 (0.57) | ALDH1A1HSD17B10DDX3XTP53ATP4A | |
| SCHEMBL7907728 | 0.71 | RARB (0.46) | ALDH1A1LMNARAB9ANPC1HSD17B10 | |
| SCHEMBL947523 | 0.71 | ALDH1A1 (0.75) | ALDH1A1LMNARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003955-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-06-01 | — | — | EP | disclosed |