Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740270 | 1.00 | LMNA (0.43) | LMNAMAPTCASP1SMN1; SMN2FLT3 | |
| SCHEMBL1456921 | 0.85 | LMNA (0.59) | LMNAMAPTCASP1SMN1; SMN2FLT3 | |
| SCHEMBL240423 | 0.79 | RAB9A (0.50) | LMNACASP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL256008 | 0.79 | HSD11B1 (0.48) | LMNAMAPTCASP1SMN1; SMN2RAB9A | |
| SCHEMBL30402035 | 0.79 | RAB9A (0.50) | LMNACASP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2494286 | 0.78 | IDO1 (0.53) | GSK3BIDO1KMT2AMEN1HTT | |
| SCHEMBL1456362 | 0.77 | ALDH1A1 (0.46) | LMNAMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13458074 | 0.76 | SMN1; SMN2 (0.47) | LMNAMAPTCASP1SMN1; SMN2RAB9A | |
| SCHEMBL21623948 | 0.76 | ATM (0.38) | LMNAMAPTCYP3A4KMT2AMEN1 | |
| SCHEMBL3152568 | 0.76 | KDM4E (0.42) | LMNAMAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872976-B | Quinoline derivative, pharmaceutical composition containing quinoline derivative and application of pharmaceutical composition | 中国药科大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115872976-A | Quinoline derivative, pharmaceutical composition containing quinoline derivative and application of quinoline derivative | 中国药科大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-108200760-B | Benzodiazepine derivatives as RSV inhibitors | 英安塔制药有限公司 | 2022-04-01 | — | — | CN | disclosed |