Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.61 |
| ▸ | TOP1 | P11387 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376699 | 1.00 | CHRNA7 (0.62) | CHRNA7CYP2D6HSD17B10ADRA2CTOP1 | |
| SCHEMBL21307810 | 1.00 | CHRNA7 (0.62) | CHRNA7CYP2D6HSD17B10ADRA2CTOP1 | |
| SCHEMBL1538791 | 1.00 | CHRNA7 (0.62) | CHRNA7CYP2D6HSD17B10ADRA2CTOP1 | |
| SCHEMBL2362454 | 1.00 | CHRNA7 (0.62) | CHRNA7CYP2D6HSD17B10ADRA2CTOP1 | |
| SCHEMBL24240060 | 0.99 | CHRNA7 (0.61) | CHRNA7CYP2D6HSD17B10ADRA2CTOP1 | |
| SCHEMBL24240057 | 0.86 | CYP2D6 (0.65) | CYP2D6HSD17B10ADRA2CTOP1ADRA1A | |
| SCHEMBL20460264 | 0.86 | CYP2D6 (0.65) | CYP2D6HSD17B10ADRA2CTOP1ADRA1A | |
| SCHEMBL11216489 | 0.85 | ADRA2A (0.64) | CHRNA7CYP2D6HSD17B10ADRA2CTOP1 | |
| SCHEMBL452289 | 0.81 | CYP2D6 (0.62) | CYP2D6HSD17B10ADRA2CTOP1ADRA1A | |
| SCHEMBL452288 | 0.81 | CYP2D6 (0.62) | CYP2D6HSD17B10ADRA2CTOP1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004790-A | Synthesis method of spiro oxindole, ke Nayin and yohimbine alkaloid and derivatives thereof | 中国科学院昆明植物研究所 | 2025-05-16 | — | — | CN | disclosed |
| CN-119086763-A | Method for simultaneously and rapidly determining gelsemium alkaloids based on MALDI-TOF MS | 华南农业大学 | 2024-12-06 | — | — | CN | disclosed |
| US-20240084272-A1 | CYTOCHROME P450 MONOOXYGENASES AND USES THEREOF | UNIV BRITISH COLUMBIA (CA) | 2024-03-14 | — | — | US | disclosed |
| US-20230248737-A1 | COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF | PSYRX LTD. (IL) | 2023-08-10 | — | — | US | disclosed |
| EP-4175643-A1 | COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF | Psyrx Ltd. (IL) | 2023-05-10 | — | — | EP | disclosed |
| US-20220347185-A1 | IBOGAINE FORMULATIONS | CAAMTECH INC (US) | 2022-11-03 | — | — | US | disclosed |
| WO-2022120490-A1 | CYTOCHROME P450 MONOOXYGENASES AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220347185-A1 | IBOGAINE FORMULATIONS | OPRK1, OPRL1, OPRD1 | CHRNA7 9/4885CYP2D6 380/4885HSD17B10 3892/4885 |
| US-20240084272-A1 | CYTOCHROME P450 MONOOXYGENASES AND USES THEREOF | CYP3A43, CYP11B2, CYP11B1 | CHRNA7 2062/4885CYP2D6 12/4885HSD17B10 118/4885 |
| US-20230248737-A1 | COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF | GRIN2C, HTR5A, HTR2A | CHRNA7 46/4885CYP2D6 644/4885HSD17B10 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.