Sugi Predict

Sugi Predict / Compounds / SCHEMBL2966567

SCHEMBL2966567

SCHEMBL2966567

CCCCN(C)CC(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.50
▸ GGPS1 O95749 3/20 0.44
▸ DNM1 Q05193 3/20 0.36
▸ KDM4C Q9H3R0 6/20 0.33
▸ KDM5A P29375 4/20 0.33
▸ S1PR2 O95136 1/20 0.33
▸ S1PR1 P21453 1/20 0.33
▸ S1PR3 Q99500 1/20 0.33
▸ S1PR5 Q9H228 1/20 0.33
▸ KDM4A O75164 2/20 0.32
▸ PHF8 Q9UPP1 1/20 0.32
▸ PLA2G1B P04054 1/20 0.31
▸ PLA2G2A P14555 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13046294 0.95 PIK3CD (0.46) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL20163315 0.92 PIK3CD (0.43) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL14473737 0.92 GGPS1 (0.52) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL23696535 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL10889894 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL10226401 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL23842241 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL22861930 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL22861625 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A
SCHEMBL8904737 0.90 GGPS1 (0.55) PIK3CDGGPS1DNM1KDM4CKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230398223-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-12-14 — — US disclosed
US-11655238-B2 MMPL3 inhibitors, compositions and uses thereof SHANGHAITECH UNIVERSITY (CN) 2023-05-23 — — US disclosed
US-20230143612-A1 SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME ARBUTUS BIOPHARMA CORP (US) 2023-05-11 — — US disclosed
US-11548870-B2 Compounds useful as inhibitors of helios protein BRISTOL-MYERS SQUIBB COMPANY (US) 2023-01-10 — — US disclosed
US-20210147383-A1 COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN BRISTOL-MYERS SQUIBB COMPANY 2021-05-20 — — US disclosed
EP-2565182-B1 NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE MITSUBISHI TANABE PHARMA CORP (JP) 2017-10-11 — — EP disclosed
EP-1921077-B1 AGENT FOR TREATING AND/OR PREVENTING SLEEP DISORDER KYOWA HAKKO KIRIN CO LTD (JP) 2017-07-26 — — EP disclosed
US-9701628-B2 12-epi pleuromutilins NABRIVA THERAPEUTICS AG (AT) 2017-07-11 — — US disclosed
EP-2646043-B1 NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION S&T GLOBAL INC (US) 2017-02-15 — — EP disclosed
US-20160052972-A1 NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION S&T GLOBAL INC. 2016-02-25 — — US disclosed
WO-2001079182-A1 2-PHENYL-2H-PYRIDAZINE-3-ONES BASF AKTIENGESELLSCHAFT (DE) 2001-10-25 — — WO disclosed
WO-2001044204-A1 PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-06-21 — — WO disclosed
US-6232470-B1 AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 2001-05-15 — — US disclosed
US-6197973-B1 HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 — — US disclosed
WO-2001012625-A2 SUBSTITUTED BENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-02-22 — — WO disclosed
US-6165944-A 4-(3-heterocyclyl-1-benzoyl) pyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2000-12-26 — — US disclosed
EP-1047693-A1 HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2000-11-02 — — EP disclosed
WO-1999031091-A1 HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1999-06-24 — — WO disclosed
US-4760064-A Cardiotonic agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-07-26 — — US disclosed
US-3983175-A FROM ORGANIC HALIDE AND A KETONE KURARAY CO., LTD. (JA) 1976-09-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160052972-A1 NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION HAVCR2, TSLP, ICOS PIK3CD 3271/4885GGPS1 2218/4885DNM1 2731/4885
US-11655238-B2 MMPL3 inhibitors, compositions and uses thereof TIMP3, AFG3L2, MMP3 PIK3CD 2498/4885GGPS1 1512/4885DNM1 707/4885
US-20210147383-A1 COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN IKZF2, RPL6, HNRNPR PIK3CD 3835/4885GGPS1 4123/4885DNM1 2993/4885
US-20230398223-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 PIK3CD 321/4885GGPS1 2757/4885DNM1 4044/4885
US-20230143612-A1 SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME HAVCR2, HMBS, VHL PIK3CD 2759/4885GGPS1 1129/4885DNM1 1168/4885
US-11548870-B2 Compounds useful as inhibitors of helios protein IKZF2, RPL6, HNRNPR PIK3CD 3835/4885GGPS1 4123/4885DNM1 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.