Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.52 |
| ▸ | NQO2 | P16083 | 3/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966642 | 1.00 | RXFP1 (0.72) | RXFP1NR1H3NR1H2NQO2TTR | |
| SCHEMBL2973560 | 0.84 | RXFP1 (1.00) | RXFP1NR1H3KDM4EMAPTALDH1A1 | |
| SCHEMBL6687632 | 0.78 | RXFP1 (0.71) | RXFP1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL18669183 | 0.74 | GAA (0.78) | RXFP1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL9387548 | 0.74 | RAB9A (0.60) | RXFP1KDM4EHPGDRAB9AGAA | |
| SCHEMBL30761909 | 0.73 | CASP3 (0.66) | KDM4EMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL30761908 | 0.73 | CASP3 (0.66) | KDM4EMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL27377656 | 0.73 | CASP3 (0.66) | KDM4EMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL8647843 | 0.73 | ALDH1A1 (0.65) | RXFP1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL6675911 | 0.72 | RXFP1 (0.62) | RXFP1KDM4EMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781580-B2 | Stilbene derivatives as new cancer therapeutic agents | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2010-08-24 | — | — | US | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | HDGF, TIE1, VEGFA | RXFP1 1236/4885NR1H3 1593/4885NR1H2 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.