Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21463379 | 0.81 | HCAR3 (0.43) | HCAR3RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12421885 | 0.78 | HCAR3 (0.58) | HCAR3RAB9ANPC1LMNAPOLB | |
| SCHEMBL31132967 | 0.78 | HCAR3 (0.58) | HCAR3RAB9ANPC1LMNAPOLB | |
| SCHEMBL26935726 | 0.76 | HCAR3 (0.40) | HCAR3POLBSLC9A1ENPP2 | |
| SCHEMBL12380478 | 0.75 | RAB9A (0.38) | HCAR3RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL24469888 | 0.73 | HCAR3 (0.36) | HCAR3RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12380477 | 0.71 | HCAR3 (0.46) | HCAR3RAB9ANPC1LMNA | |
| SCHEMBL17559067 | 0.70 | HCAR3 (0.54) | HCAR3RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3653470 | 0.67 | LPL (0.49) | ENPP2DUT | |
| SCHEMBL3866189 | 0.66 | DUT (0.35) | ENPP2DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |