Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420259 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL6896294 | 0.91 | PRSS1 (0.53) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL17743314 | 0.88 | PRSS1 (0.56) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL420519 | 0.88 | MAPT (0.54) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL26324521 | 0.84 | HCAR3 (0.63) | ALDH1A1PKMMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL15206115 | 0.84 | APEX1 (0.61) | ALDH1A1PKMMAPTRAB9AKMT2A | |
| SCHEMBL563763 | 0.83 | PKM (0.67) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL29410422 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL29392416 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL24055 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |