Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670495 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL6896294 | 0.91 | PRSS1 (0.53) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL17743314 | 0.88 | PRSS1 (0.56) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL420519 | 0.88 | MAPT (0.54) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL26324521 | 0.84 | HCAR3 (0.63) | ALDH1A1PKMMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL15206115 | 0.84 | APEX1 (0.61) | ALDH1A1PKMMAPTRAB9AKMT2A | |
| SCHEMBL563763 | 0.83 | PKM (0.67) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL29410422 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL29392416 | 0.83 | ALDH1A1 (0.68) | ALDH1A1TSHRTDP1PKMMAPT | |
| SCHEMBL24055 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | claimed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | claimed |
| US-9499419-B2 | Methods and compositions for treatment of skin | Special Waters Patents B.V. (NL) | 2016-11-22 | — | — | US | disclosed |
| US-9237999-B2 | Cosmetic or pharmaceutical composition comprising modified polyorganosiloxanes | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2016-01-19 | — | — | US | disclosed |
| US-8993765-B2 | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130344021-A1 | Cosmetic Or Pharmaceutical Composition Comprising Modified Polyorganosiloxanes | CLARIANT GMBH (DE) | 2013-12-26 | — | — | US | disclosed |
| US-8404670-B2 | Histamine H3 inverse agonists and antagonists and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-8404670-B2 | Histamine H3 inverse agonists and antagonists and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-8404670-B2 | Histamine H3 inverse agonists and antagonists and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2013-03-26 | — | — | US | disclosed |
| EP-1576945-B1 | Cosmetic or pharmaceutic composition comprising modified polyorganosiloxane | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2012-12-19 | — | — | EP | disclosed |
| CN-102065835-B | Cosmetic or pharmaceutical compositions comprising modified polysiloxanes with at least one carbamate group | CLARIANT INT LTD | 2012-11-28 | — | — | CN | disclosed |
| EP-1647267-A1 | Cosmetic, dermatological and pharmaceutical compositions | Clariant Produkte (Deutschland) GmbH (DE) | 2006-04-19 | — | — | EP | disclosed |
| US-20050255075-A1 | Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes | CLARIANT GMBH | 2005-11-17 | — | — | US | disclosed |
| US-20050204484-A1 | Hair colorants | CLARIANT GMBH | 2005-09-22 | — | — | US | disclosed |
| EP-1576945-A1 | Cosmetic or pharmaceutic composition comprising modified polyorganosiloxane | Clariant GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| EP-1555012-A1 | Hair dyeing composition containing anthraquinones | Clariant GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | disclosed |
| US-4835314-A | 2-nitroaniline derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130344021-A1 | Cosmetic Or Pharmaceutical Composition Comprising Modified Polyorganosiloxanes | POLH, SGMS2, SGMS1 | ALDH1A1 3115/4885TSHR 2695/4885TDP1 1140/4885 |
| US-20050204484-A1 | Hair colorants | MC1R, CYB5R3, AR | ALDH1A1 925/4885TSHR 1543/4885TDP1 4597/4885 |
| US-20050255075-A1 | Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes | POLH, SGMS2, SGMS1 | ALDH1A1 3087/4885TSHR 2675/4885TDP1 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.