Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | STAT5B | P51692 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452031 | 0.87 | LMNA (0.42) | MMP2MMP9LMNAKDM4ETP53 | |
| SCHEMBL8588375 | 0.87 | MIF (0.38) | — | |
| SCHEMBL2378054 | 0.85 | SMN1; SMN2 (0.39) | MMP2MMP9LMNAKDM4ETP53 | |
| SCHEMBL27498638 | 0.85 | MT-CO2 (0.48) | MMP2MMP9LMNAKDM4ETP53 | |
| SCHEMBL29950836 | 0.83 | ENPP2 (0.42) | KDM4E | |
| SCHEMBL21401590 | 0.79 | MT-CO2 (0.47) | LMNASTAT5B | |
| SCHEMBL14798322 | 0.78 | CA1 (0.43) | LMNAKEAP1 | |
| SCHEMBL14384381 | 0.77 | PAX8 (0.50) | LMNAMAPT | |
| SCHEMBL28154669 | 0.77 | PAX8 (0.36) | F2 | |
| SCHEMBL7085046 | 0.77 | CNR2 (0.44) | TP53F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |