Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153673 | 0.84 | PAX8 (0.35) | PAX8CA12CA1CA2CA9 | |
| SCHEMBL8588375 | 0.77 | MIF (0.38) | PAX8CA12CA1CA2CA9 | |
| SCHEMBL2968367 | 0.77 | MMP2 (0.41) | F2 | |
| SCHEMBL2378054 | 0.76 | SMN1; SMN2 (0.39) | PAX8SMN1; SMN2MT-CO2HSP90AA1 | |
| SCHEMBL27498638 | 0.76 | MT-CO2 (0.48) | SMN1; SMN2MT-CO2HSP90AA1 | |
| SCHEMBL29950836 | 0.73 | ENPP2 (0.42) | PAX8CA12CA1CA2CA9 | |
| SCHEMBL5187166 | 0.73 | KDM4E (0.37) | PAX8F2SMN1; SMN2 | |
| SCHEMBL30978116 | 0.70 | USP30 (0.31) | GPR119CYP17A1 | |
| SCHEMBL21854444 | 0.70 | USP30 (0.31) | GPR119CYP17A1 | |
| SCHEMBL14798322 | 0.69 | CA1 (0.43) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715419-A | Aminotriazine derivatives as TANK-binding kinase inhibitor compounds | 吉利德科学公司 | 2017-05-24 | — | — | CN | disclosed |