Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692255 | 0.90 | HDAC1 (0.47) | ELANEGPR139ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9943346 | 0.84 | GAA (0.58) | GPR139ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27535714 | 0.84 | L3MBTL1 (0.49) | ELANEALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1686722 | 0.84 | GAA (0.58) | GPR139ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2968424 | 0.83 | MTNR1A (0.54) | ELANEALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11066914 | 0.82 | ALDH1A1 (0.49) | ELANEALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8583451 | 0.81 | MAPK1 (0.49) | ELANEALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6250510 | 0.81 | MAPK1 (0.49) | ELANEALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12849869 | 0.80 | RAB9A (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18285011 | 0.80 | GAA (0.50) | GPR139ALDH1A1SMN1; SMN2KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164389-B1 | PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1987-04-01 | — | — | EP | disclosed |
| EP-0164389-A1 | PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1985-12-18 | — | — | EP | disclosed |
| WO-1985002609-A1 | PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1985-06-20 | — | — | WO | disclosed |