SCHEMBL296847

SCHEMBL296847

C1=C(C2=CCCCCC2)CCCCC1.CCO[Si](C)(C)CC

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
PSMB5 P28074 9/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ELANE P08246 1/20 0.33
PTGS2 P35354 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31
PSMB1 P20618 1/20 0.31
KCNH2 Q12809 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4325254 0.84 JAK2 (0.34) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL295858 0.84 ALDH1A1 (0.37) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL295851 0.78 ALDH1A1 (0.37) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL21722770 0.76 JAK2 (0.35) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL2103129 0.76 PSMB5 (0.37) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL1585575 0.75 JAK2 (0.31) JAK2JAK3
SCHEMBL2275575 0.75 PSMB5 (0.32) JAK2JAK3PSMB5
SCHEMBL336090 0.75 RAB9A (0.37) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL2369821 0.74 JAK2 (0.32) JAK2JAK3PSMB5ALDH1A1CYP3A4
SCHEMBL12979868 0.73 PSMB5 (0.36) JAK2JAK3PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP disclosed
EP-1833880-B1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC CORP (JP) 2012-03-14 EP disclosed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US disclosed
US-7915369-B2 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2011-03-29 US disclosed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP disclosed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP disclosed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO disclosed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US disclosed