Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134933 | 1.00 | MAPT (0.41) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL20134983 | 0.91 | ADAMTS5 (0.37) | MAPTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL29688815 | 0.91 | ADAMTS5 (0.37) | MAPTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL29688842 | 0.88 | LMNA (0.44) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL20135127 | 0.88 | LMNA (0.44) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL29689268 | 0.88 | LMNA (0.44) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL20135123 | 0.88 | LMNA (0.44) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL20135401 | 0.88 | LMNA (0.44) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL29689282 | 0.88 | LMNA (0.44) | MAPTSMN1; SMN2GAAATMLMNA | |
| SCHEMBL20134817 | 0.85 | ALDH1A1 (0.37) | MAPTSMN1; SMN2LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | claimed |
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |