Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 1/20 | 0.69 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441847 | 0.93 | UGT1A1 (0.71) | UGT1A1UGT1A8MAPTCYP3A4SMN1; SMN2 | |
| Irisone A SCHEMBL571686 | 0.84 | UGT1A1 (0.64) | UGT1A1UGT1A8MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL12073700 | 0.82 | UGT1A1 (1.00) | UGT1A1UGT1A8MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL1114843 | 0.80 | ABCG2 (0.62) | MAPTABCB1MEN1KMT2AKDM4E | |
| SCHEMBL30708523 | 0.80 | EGFR (0.76) | MAPTCYP3A4SMN1; SMN2ALDH1A1ABCB1 | |
| 3'-O-Methylorobol SCHEMBL30380427 | 0.78 | MAPT (0.73) | MAPTCYP3A4SMN1; SMN2ALDH1A1ABCB1 | |
| 3'-O-Methylorobol SCHEMBL30380012 | 0.78 | MAPT (0.73) | MAPTCYP3A4SMN1; SMN2ALDH1A1ABCB1 | |
| 3'-O-Methylorobol SCHEMBL13730131 | 0.78 | MAPT (0.73) | MAPTCYP3A4SMN1; SMN2ALDH1A1ABCB1 | |
| Irisolone SCHEMBL242540 | 0.78 | UGT1A1 (0.73) | UGT1A1UGT1A8MAPTCYP3A4SMN1; SMN2 | |
| Irisolone SCHEMBL29928854 | 0.78 | UGT1A1 (0.73) | UGT1A1UGT1A8MAPTCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992467-B2 | Promotion of lymphatic function | UNIVERSITAET BASEL (CH) | 2024-05-28 | — | — | US | disclosed |
| US-20220175696-A1 | PROMOTION OF LYMPHATIC FUNCTION | UNIVERSITAET BASEL (CH) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992467-B2 | Promotion of lymphatic function | LTA, LRBA, RALA | UGT1A1 1637/4885UGT1A8 1329/4885MAPT 2232/4885 |
| US-20220175696-A1 | PROMOTION OF LYMPHATIC FUNCTION | LTA, LRBA, RALA | UGT1A1 1637/4885UGT1A8 1329/4885MAPT 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.