SCHEMBL12073700

SCHEMBL12073700

O=c1c(-c2ccc(O)cc2)coc2cc3c(c(O)c12)OCO3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT1A1 P22309 2/20 1.00
UGT1A8 Q9HAW9 1/20 1.00
MAPT P10636 10/20 0.56
TP53 P04637 8/20 0.56
CYP3A4 P08684 8/20 0.56
HPGD P15428 8/20 0.56
MEN1 O00255 8/20 0.56
KMT2A Q03164 8/20 0.56
SMN1; SMN2 Q16637 8/20 0.56
ALDH1A1 P00352 7/20 0.56
NPC1 O15118 6/20 0.56
RAB9A P51151 6/20 0.56
ALOX15 P16050 5/20 0.56
MAPK1 P28482 4/20 0.56
CYP2C9 P11712 4/20 0.56
CYP2C19 P33261 4/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
CYP1A2 P05177 3/20 0.56
ESR1 P03372 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Irisolone SCHEMBL242540 0.85 UGT1A1 (0.73) UGT1A1UGT1A8MAPTTP53CYP3A4
Irisolone SCHEMBL29928854 0.85 UGT1A1 (0.73) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL29441847 0.83 UGT1A1 (0.71) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL29696493 0.82 UGT1A1 (0.69) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL7760763 0.79 PPARG (0.70) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL6412437 0.79 UGT1A1 (0.65) UGT1A1UGT1A8MAPTTP53CYP3A4
Irisone A SCHEMBL571686 0.78 UGT1A1 (0.64) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL13279932 0.77 MAPT (0.75) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL30525493 0.77 MAPT (0.75) UGT1A1UGT1A8MAPTTP53CYP3A4
SCHEMBL17718213 0.74 EGFR (0.63) UGT1A1UGT1A8MAPTTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
US-20250009655-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC 2025-01-09 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2023150072-A1 COMPOSITIONS AND METHODS FOR THE PRESERVATION OF PLANT MATTER SINCLAIR DAVID A (US) 2023-08-10 WO claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
CN-115957232-A Anti-aging, anti-glycosylation, antioxidant and anti-inflammatory cell nano-product and preparation method and application thereof 广州辛选供应链有限公司 2023-04-14 CN claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
CN-115429821-A Compound probiotic composition for preventing dental caries and regulating intestinal flora and immunity and preparation method and application thereof 北京科拓恒通生物技术股份有限公司 2022-12-06 CN claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
CN-114796236-A Composition for treating dementia 史蒂文·霍夫曼 2022-07-29 CN claimed
CN-114306183-A Novel use of plant-derived alkaline phosphatase expression promoter 香港科技大学 2022-04-12 CN claimed
CN-114272346-A Foot health product for treating rheumatoid arthritis 苏州大学 2022-04-05 CN claimed
EP-4190172-B1 SWEETENER COMPOSITION COMPRISING STEVIOL GLYCOSIDE SWEETENERS WITH IMPROVED FLAVOR PROFILES COCA COLA CO (US) 2025-11-26 EP disclosed
US-12390418-B2 Biphasic compositions comprising one or both of carbonate and phosphate Natural Extraction Systems, LLC (US) 2025-08-19 US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 US disclosed
CN-113274475-B Traditional Chinese medicine for treating rheumatoid arthritis 苏州大学 2022-02-22 CN disclosed
WO-2011163241-A2 NEUROPROTECTIVE COMPOUNDS GEORGETOWN UNIVERSITY (US) 2011-12-29 WO disclosed
CN-100569241-C Celery seed acetic acid ethyl ester extract and uses thereof BEIJING TIANCHUN JUNWEI MEDICI (CN) 2009-12-16 CN disclosed
CN-101007015-A Application of flavonoids of celery seed and coumarins in preparation of drug for preventing and treating gout BEIJING TIANCHUN JUNWEI MEDICI (CN) 2007-08-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB UGT1A1 1445/4885UGT1A8 1189/4885MAPT 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.