Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 1/20 | 0.73 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.73 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Irisolone SCHEMBL242540 | 1.00 | UGT1A1 (0.73) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| SCHEMBL12073700 | 0.85 | UGT1A1 (1.00) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| SCHEMBL30471499 | 0.84 | UGT1A1 (0.52) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| Irisflorentin SCHEMBL29285415 | 0.84 | ALDH1A1 (0.53) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| SCHEMBL31475104 | 0.78 | ALDH1A1 (0.52) | UGT1A1UGT1A8KDM4ESMN1; SMN2MAPT | |
| SCHEMBL29441847 | 0.78 | UGT1A1 (0.71) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| SCHEMBL29696493 | 0.78 | UGT1A1 (0.69) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| Tectorigenin SCHEMBL351641 | 0.76 | EGFR (1.00) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| Tectorigenin SCHEMBL29353966 | 0.76 | EGFR (1.00) | UGT1A1UGT1A8EGFRKDM4EPOLB | |
| SCHEMBL28274172 | 0.75 | KDM4E (0.67) | EGFRKDM4EPOLBALDH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009655-A1 | BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE | Natural Extraction Systems, LLC | 2025-01-09 | — | — | US | claimed |
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| WO-2023064318-A1 | BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE | Natural Extraction Systems, LLC (US) | 2023-04-20 | — | — | WO | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| US-12390418-B2 | Biphasic compositions comprising one or both of carbonate and phosphate | Natural Extraction Systems, LLC (US) | 2025-08-19 | — | — | US | disclosed |
| US-20250009655-A1 | BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE | Natural Extraction Systems, LLC | 2025-01-09 | — | — | US | disclosed |
| US-20240245600-A1 | ORRIS ROOT EXTRACTS, COMPOSITIONS, AND METHODS FOR SKIN APPLICATIONS | ACCESS BUSINESS GROUP INT LLC (US) | 2024-07-25 | — | — | US | disclosed |
| CN-117883454-A | Application of 25-hydroxycholesterol in preparation of macrophage scavenger receptor 1 inhibiting medicine | 浙江大学医学院附属第一医院 | 2024-04-16 | — | — | CN | disclosed |
| CN-116725998-A | Application of teriflunomide in inhibiting NLRP3 inflammatory body activation | 中国科学技术大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-113880820-B | Butenolide derivative and application thereof, and pharmaceutical composition | 云南大学 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022256476-A1 | ORRIS ROOT EXTRACTS, COMPOSITIONS, AND METHODS FOR SKIN APPLICATIONS | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2022-12-08 | — | — | WO | disclosed |
| CN-115429792-A | Application of wedelolactone in preparation of inflammation corpuscle activation inhibitor or medicine for treating gouty arthritis | 东莞广州中医药大学研究院 | 2022-12-06 | — | — | CN | disclosed |