SCHEMBL29441847

SCHEMBL29441847

COc1ccc(-c2coc3cc4c(c(O)c3c2=O)OCO4)cc1OC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT1A1 P22309 1/20 0.71
UGT1A8 Q9HAW9 1/20 0.71
ABCB1 P08183 1/20 0.60
MAPT P10636 8/20 0.57
CYP3A4 P08684 5/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
ALDH1A1 P00352 3/20 0.57
NPC1 O15118 6/20 0.54
RAB9A P51151 6/20 0.54
KDM4E B2RXH2 5/20 0.54
TP53 P04637 4/20 0.54
MAPK1 P28482 3/20 0.54
HSD17B10 Q99714 3/20 0.54
POLB P06746 2/20 0.50
HPGD P15428 2/20 0.49
LMNA P02545 2/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696493 0.93 UGT1A1 (0.69) UGT1A1UGT1A8ABCB1MAPTCYP3A4
Irisone A SCHEMBL571686 0.85 UGT1A1 (0.64) UGT1A1UGT1A8ABCB1MAPTCYP3A4
SCHEMBL12073700 0.83 UGT1A1 (1.00) UGT1A1UGT1A8ABCB1MAPTCYP3A4
SCHEMBL29887713 0.79 EGFR (0.76) ABCB1MAPTCYP3A4SMN1; SMN2ALDH1A1
Irisolone SCHEMBL29928854 0.78 UGT1A1 (0.73) UGT1A1UGT1A8ABCB1MAPTCYP3A4
Irisolone SCHEMBL242540 0.78 UGT1A1 (0.73) UGT1A1UGT1A8ABCB1MAPTCYP3A4
Irisflorentin SCHEMBL29285415 0.78 ALDH1A1 (0.53) UGT1A1UGT1A8ABCB1MAPTCYP3A4
SCHEMBL30380678 0.76 ABCB1 (0.76) ABCB1MAPTCYP3A4SMN1; SMN2ALDH1A1
SCHEMBL28740045 0.74 PTPN1 (0.70) ABCB1MAPTCYP3A4SMN1; SMN2ALDH1A1
SCHEMBL30288208 0.73 CYP3A4 (0.81) ABCB1MAPTCYP3A4SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240390445-A1 METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2024-11-28 US claimed
EP-4408196-A1 A METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2024-08-07 EP claimed
CN-118042938-A A method for treating cancer 天然成分与健康研究组织 2024-05-14 CN claimed
WO-2023049970-A1 A METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2023-04-06 WO claimed
CN-115517216-A Ecological culture pond of elodea furrow planting surface bed method 浙江米果果生态农业集团有限公司 2022-12-27 CN claimed
CN-115346600-A Red tide early warning method for ceratophyllum angulatum 大连理工大学盘锦产业技术研究院 2022-11-15 CN claimed
CN-115317503-A Oral spray and preparation method thereof 乐比(广州)健康产业有限公司 2022-11-11 CN claimed
EP-3701034-B1 STRIPE RUST RESISTANCE GENE WTK1 (YR15) AND USE THEREOF CARMEL HAIFA UNIV ECONOMIC CORPORATION LTD (IL) 2026-04-08 EP disclosed
US-20250161182-A1 ANTIMICROBIAL COMPOSITIONS BIO-ACTIVES SYNERGIO LTD (IL) 2025-05-22 US disclosed
EP-4469037-A1 ANTIMICROBIAL COMPOSITIONS Bio-Actives Synergio Ltd (IL) 2024-12-04 EP disclosed
US-20240390445-A1 METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2024-11-28 US disclosed
CN-118829356-A Methods and compositions for controlling pests UPL有限责任公司 2024-10-22 CN disclosed
CN-118660702-A Antimicrobial compositions 生物活性协同有限公司 2024-09-17 CN disclosed
CN-114921346-A Heterosporangium allochrum APS-1 and application thereof 山东省花生研究所 2022-08-19 CN disclosed
CN-114766268-A Method for preventing and treating lygus palmatus 田菲菲 2022-07-22 CN disclosed
CN-114766268-A Method for preventing and treating lygus palmatus 田菲菲 2022-07-22 CN disclosed
US-20220217901-A1 NUTRIENT COMPOSITIONS FOR CULTIVATING SPHAGNUM Micropropagation Services (E.M.) Limited (GB) 2022-07-14 US disclosed
CN-114384165-A Quality control method of Guilong ointment 广西邦琪药业集团有限公司 2022-04-22 CN disclosed
WO-2022056588-A1 TOPICAL AQUEOUS SANITIZER FORMULATION HGWIT Pty Ltd (AU) 2022-03-24 WO disclosed
CN-114195772-A 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit and preparation method and application thereof 贵州大学 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161182-A1 ANTIMICROBIAL COMPOSITIONS NOD2, PYCARD, CLPP UGT1A1 1439/4885UGT1A8 515/4885ABCB1 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.