Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 3/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616864 | 0.87 | MMP8 (0.44) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL982864 | 0.83 | LMNA (0.55) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL28759248 | 0.82 | CYP1A2 (0.43) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL11847693 | 0.79 | LMNA (0.50) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL31079040 | 0.76 | LMNA (0.50) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL280235 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1CYP2C9MEN1KMT2A | |
| SCHEMBL6675458 | 0.73 | CES2 (0.56) | KDM4EMEN1KMT2AMAPTGRM8 | |
| SCHEMBL2484700 | 0.73 | CES2 (0.56) | KDM4EMEN1KMT2AMAPTGRM8 | |
| SCHEMBL13924144 | 0.72 | SMN1; SMN2 (0.50) | LMNAALDH1A1HTTKDM4EMEN1 | |
| SCHEMBL13557323 | 0.70 | MEN1 (0.47) | LMNACYP1A2ALDH1A1HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135628-A | Compounds for fast and efficient click release | 泰克沃尔科斯制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-114599645-A | Reagents for cleaving a label from a biomolecule in vivo | 泰克沃尔科斯制药有限公司 | 2022-06-07 | — | — | CN | disclosed |