SCHEMBL2970016

SCHEMBL2970016

FC(F)C(F)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.41
TSHR P16473 1/20 0.41
CA4 P22748 1/20 0.38
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
NPC1 O15118 1/20 0.35
ALOX15 P16050 1/20 0.35
RAB9A P51151 1/20 0.35
KCNA3 P22001 1/20 0.35
KDM4E B2RXH2 2/20 0.34
SLC6A4 P31645 1/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
TEAD4 Q15561 1/20 0.33
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6466375 0.86 DRD1 (0.37) MAPTALDH1A1NPC1ALOX15RAB9A
SCHEMBL153060 0.78 ALDH1A1 (0.50) LTA4HTSHRCA4MAPTALDH1A1
SCHEMBL10600901 0.76 KMT2A (0.35) CA4ALDH1A1KMT2A
SCHEMBL29153373 0.75 LMNA (0.33) TSHRMAPTALDH1A1SLC6A4KMT2A
SCHEMBL3732313 0.75 MEN1 (0.46) LTA4HCA4MAPTALDH1A1NPC1
SCHEMBL27295407 0.75 SLC6A4 (0.40) LTA4HTSHRCA4MAPTALDH1A1
SCHEMBL17134135 0.75
SCHEMBL10602962 0.75 PPARG (0.39) SLC6A4KMT2AMEN1PPARGPPARA
SCHEMBL28384768 0.75 LDHA (0.47) MAPTALDH1A1ALOX15RAB9AKDM4E
SCHEMBL29138027 0.75 SCN4A (0.39) LTA4HTSHRKCNA3SLC6A4MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117940612-A Method and apparatus for enriching substrates with alkali metals and electrolytes 雷纳技术有限责任公司 2024-04-26 CN claimed
CN-116864809-A Lithium ion battery electrolyte and application thereof 远景动力技术(江苏)有限公司 2023-10-10 CN claimed
US-7763602-B2 Pyrrole derivatives as antimycobacterial compounds LUPIN LIMITED (IN) 2010-07-27 US claimed
US-7691837-B2 Pyrrole derivatives as antimycobacterial compounds LUPIN LIMITED (IN) 2010-04-06 US claimed
US-20040220409-A1 Flecainide synthesis MCDANIEL WILLIAM C 2004-11-04 US claimed
WO-2002066413-A1 FLECAINIDE SYNTHESIS NARCHEM CORPORATION (US) 2002-08-29 WO claimed
CN-117940612-A Method and apparatus for enriching substrates with alkali metals and electrolytes 雷纳技术有限责任公司 2024-04-26 CN disclosed
CN-116914244-A High concentration lithium ion electrolyte for battery cells 苹果公司 2023-10-20 CN disclosed
CN-116864809-A Lithium ion battery electrolyte and application thereof 远景动力技术(江苏)有限公司 2023-10-10 CN disclosed
CN-116670883-A Rechargeable battery 麻省固能控股有限公司 2023-08-29 CN disclosed
CN-116210105-A 2, 5-dimercapto-1, 3, 4-thiadiazole ('DMTD') metal salt derivatives 路博润公司 2023-06-02 CN disclosed
CN-109790091-B Substituted bis (trifluorovinyl) benzene compounds 东曹精细化工株式会社 2021-06-15 CN disclosed
EP-3521266-B1 SUBSTITUTED BIS(TRIFLUOROVINYL)BENZENE COMPOUND TOSOH FINECHEM CORP (JP) 2021-03-24 EP disclosed
US-4534788-A CONTROLLING WEEDS IN WHEAT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-13 US disclosed
EP-0064322-B1 BENZENESULFONYL ISOCYANATES, ISOTHIOCYANATES, CHLORIDES, AND SULFONAMIDES HAVING A FLUORINATED SUBSTITUENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-05-22 EP disclosed
US-4452628-A TRIAZINYL BENZENE SULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-05 US disclosed
EP-0023422-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-22 EP disclosed
EP-0064322-A2 Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-10 EP disclosed
EP-0057546-A2 Sulfonylurea N-oxides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-11 EP disclosed
EP-0023422-A2 Herbicidal sulfonamides, preparation and use thereof, and compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220409-A1 Flecainide synthesis KCNH1, CYP3A43, CYP2F1 LTA4H 2975/4885TSHR 245/4885CA4 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.