Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23163619 | 0.91 | NFE2L2 (0.36) | NFE2L2IDO1MCHR1HPGDHSD11B1 | |
| SCHEMBL29705652 | 0.87 | HSD11B1 (0.43) | HSD11B1MAP4K4HSD11B2CTSLCTSS | |
| SCHEMBL23163760 | 0.78 | HSD11B1 (0.40) | HSD11B1HSD11B2 | |
| SCHEMBL2192991 | 0.78 | HSD11B1 (0.54) | NFE2L2IDO1MCHR1HPGDHSD11B1 | |
| SCHEMBL29705655 | 0.76 | LMNA (0.42) | NFE2L2IDO1MCHR1HPGDGCK | |
| SCHEMBL2195636 | 0.70 | HPGD (0.47) | NFE2L2IDO1MCHR1HPGD | |
| SCHEMBL23164049 | 0.70 | HRH3 (0.40) | NFE2L2IDO1MCHR1HPGDCXCR1 | |
| SCHEMBL23163700 | 0.70 | NFE2L2 (0.39) | NFE2L2IDO1MCHR1HPGDHSD11B1 | |
| SCHEMBL15821832 | 0.69 | MAP4K4 (0.47) | MAP4K4SLC6A4SLC6A3 | |
| SCHEMBL10351821 | 0.69 | NR1H4 (0.38) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |