Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23246323 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTALDH1A1KDM4ECYP2C9 | |
| SCHEMBL23246313 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTALDH1A1KDM4ECYP2C9 | |
| SCHEMBL28739389 | 0.91 | ALDH1A1 (0.44) | L3MBTL1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL29842235 | 0.85 | PYGL (0.45) | MAPTALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL29842354 | 0.85 | CYP17A1 (0.45) | MAPTALDH1A1KDM4ECYP2C9LMNA | |
| SCHEMBL29842108 | 0.85 | KDM4E (0.38) | L3MBTL1MAPTALDH1A1KDM4ELCK | |
| SCHEMBL10318265 | 0.84 | ALDH1A1 (0.50) | L3MBTL1MAPTALDH1A1KDM4ECYP2C9 | |
| SCHEMBL29842325 | 0.82 | ABCC9 (0.39) | ALDH1A1KDM4ELCK | |
| SCHEMBL23265853 | 0.82 | EGLN2 (0.38) | ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL28739391 | 0.82 | EGLN2 (0.38) | ALDH1A1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045494-A1 | SYNTHESIS OF 6-METHYL-N1-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)BENZENE-1,3-DIAMINE | Esco Aster Pte. Ltd. (SG) | 2022-08-24 | — | — | EP | disclosed |
| CN-114585615-A | Synthesis of 6-methyl-N1- (4- (pyridin-3-yl) pyrimidin-2-yl) benzene-1, 3-diamine | 新加坡艺思高艾斯特生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |