SCHEMBL297076

SCHEMBL297076

c1ccc(Oc2nnn[nH]2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.44
TSHR P16473 1/20 0.44
NPC1 O15118 1/20 0.38
SCN4A P35499 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4C Q9H3R0 1/20 0.37
HAO1 Q9UJM8 2/20 0.37
BCAT2 O15382 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAOA P21397 1/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
MAPT P10636 1/20 0.35
TLR8 Q9NR97 1/20 0.33
ERCC5 P28715 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743661 0.82 LTA4H (0.32) LTA4HTSHRNPC1SCN4ARAB9A
SCHEMBL9505524 0.80 ALDH1A1 (0.45) LTA4HNPC1SCN4ARAB9AHAO1
SCHEMBL14112763 0.80 ALDH1A1 (0.48) TSHRNPC1RAB9AALDH1A1MAOA
Melizame SCHEMBL1404194 0.78 KDM4C (0.45) TSHRRAB9AKDM4CALDH1A1HTT
SCHEMBL14093100 0.76 SMN1; SMN2 (0.39) NPC1RAB9AKDM4CALDH1A1MAPT
SCHEMBL3211566 0.74 CA1 (0.31)
SCHEMBL6502581 0.73 LTA4H (0.49) LTA4HTSHRNPC1SCN4ARAB9A
SCHEMBL11204093 0.73 CA2 (0.39) TSHRNPC1RAB9AALDH1A1KMT2A
SCHEMBL11205508 0.72 BACE1 (0.35)
SCHEMBL11204242 0.72 ALDH1A1 (0.42) NPC1RAB9AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759922-A1 NEW ANTAGONIST COMPOUNDS Astra Aktiebolag (SE) 1997-03-05 EP claimed
WO-1995031463-A1 NEW ANTAGONIST COMPOUNDS ASTRA AKTIEBOLAG (SE) 1995-11-23 WO claimed
CN-120441500-B 5-Phenoxy tetrazole compound, reagent and preparation method thereof and application of reagent in preparation of antitumor drugs 中国人民解放军陆军军医大学第二附属医院 2025-09-09 CN disclosed
CN-120441500-B 5-Phenoxy tetrazole compound, reagent and preparation method thereof and application of reagent in preparation of antitumor drugs 中国人民解放军陆军军医大学第二附属医院 2025-09-09 CN disclosed
CN-120441500-A 5-Phenoxy tetrazole compound, reagent and preparation method thereof and application of reagent in preparation of antitumor drugs 中国人民解放军陆军军医大学第二附属医院 2025-08-08 CN disclosed
CN-120441500-A 5-Phenoxy tetrazole compound, reagent and preparation method thereof and application of reagent in preparation of antitumor drugs 中国人民解放军陆军军医大学第二附属医院 2025-08-08 CN disclosed
EP-2331649-B1 METHODS AND COMPOSITIONS FOR POLISHING SILICON-CONTAINING SUBSTRATES CABOT MICROELECTRONICS CORP (US) 2018-06-13 EP disclosed
US-8597540-B2 Compositions for polishing silicon-containing substrates CABOT MICROELECTRONICS CORPORATION (US) 2013-12-03 US disclosed
US-20130200039-A1 AQUEOUS POLISHING COMPOSITIONS CONTAINING N-SUBSTITUTED DIAZENIUM DIOXIDES AND/OR N'-HYDROXY-DIAZENIUM OXIDE SALTS BASF SE (DE) 2013-08-08 US disclosed
EP-2613910-A1 PROCESS FOR CHEMICALLY MECHANICALLY POLISHING SUBSTRATES CONTAINING SILICON OXIDE DIELECTRIC FILMS AND POLYSILICON AND/OR SILICON NITRIDE FILMS BASF SE (DE) 2013-07-17 EP disclosed
EP-2614122-A1 AQUEOUS POLISHING COMPOSITIONS CONTAINING N-SUBSTITUTED DIAZENIUM DIOXIDES AND/OR N'-HYDROXY-DIAZENIUM OXIDE SALTS BASF SE (DE) 2013-07-17 EP disclosed
EP-0325336-A1 Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-07-26 EP disclosed
EP-0113964-B1 4-AMINOALKYL-2(3H)-INDOLONES SMITHKLINE BECKMAN CORPORATION (US) 1986-10-22 EP disclosed
US-4588740-A Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones SMITHKLINE BECKMAN CORPORATION (US) 1986-05-13 US disclosed
EP-0113964-A1 4-Aminoalkyl-2(3H)-indolones SMITHKLINE BECKMAN CORPORATION (US) 1984-07-25 EP disclosed
US-4452808-A HYPOTENSIVE AGENTS SMITHKLINE BECKMAN CORPORATION (US) 1984-06-05 US disclosed
US-4390699-A NARCOTIC ANTAGONIST THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1983-06-28 US disclosed
US-4388463-A 6-Keto-morphinan analgesics THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1983-06-14 US disclosed
EP-0034925-B1 5-(DIHYDROXYPHENOXY) TETRAZOLES AS SWEETENERS ELI LILLY AND COMPANY (US) 1983-05-04 EP disclosed
EP-0034925-A1 5-(Dihydroxyphenoxy) tetrazoles as sweeteners ELI LILLY AND COMPANY (US) 1981-09-02 EP disclosed