Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.69 |
| ▸ | ELANE | P08246 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ACLY | P53396 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303812 | 0.91 | ELANE (0.65) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL16226994 | 0.85 | ELANE (0.66) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL29361502 | 0.85 | ELANE (0.66) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL29359746 | 0.85 | ELANE (0.66) | PIM1ELANEMAPTALDH1A1KDM4E | |
| Austrocortirubin SCHEMBL23199031 | 0.84 | LCK (0.56) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL23199095 | 0.84 | ALDH1A1 (0.60) | PIM1ELANEMAPTALDH1A1KDM4E | |
| Austrocortirubin SCHEMBL29357393 | 0.84 | LCK (0.56) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL23199046 | 0.82 | PIM1 (0.66) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL23198975 | 0.82 | EPHX2 (0.65) | PIM1ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL30097984 | 0.82 | ACLY (0.71) | PIM1ELANEMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11304927-B2 | Bioactive extract, fraction of Cassia occidentalis and formulation thereof for bone regeneration | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11304927-B2 | Bioactive extract, fraction of Cassia occidentalis and formulation thereof for bone regeneration | BMP4, BMP2, BMP1 | PIM1 2182/4885ELANE 4141/4885MAPT 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.