Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL29720276

COc1cccc(C[N+](C)(C)C)c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.50
CHRM1 P11229 3/20 0.50
CHRM3 P20309 3/20 0.50
KCNH2 Q12809 1/20 0.45
ACHE P22303 1/20 0.43
CMA1 P23946 1/20 0.42
TMEM97 Q5BJF2 1/20 0.42
TAAR1 Q96RJ0 3/20 0.42
IDO1 P14902 2/20 0.42
AGXT P21549 2/20 0.42
TAS2R14 Q9NYV8 1/20 0.42
CYP19A1 P11511 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10256665 0.83 CHRM2 (0.62) CHRM2CHRM1CHRM3CMA1TAAR1
Trifluoromethanesulfonic Acid SCHEMBL1455736 0.82 PKM (0.46) KCNH2ACHECA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL29720398 0.81 GPR3 (0.46) KCNH2ACHETAAR1TAS2R14CYP19A1
Trifluoromethanesulfonic Acid SCHEMBL1130292 0.79 KDM4E (0.59) KCNH2ACHECA9ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL31031306 0.77 TDP1 (0.36) CHRM2CHRM1CHRM3KCNH2ACHE
1-Hydroxy-3-Methoxybenzene SCHEMBL7085847 0.75 KCNH2 (0.49) KCNH2ACHECA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL565741 0.73 ACHE (0.45) KCNH2ACHETAS2R14LMNAHTT
Emilium SCHEMBL122382 0.73 LMNA (0.53) CHRM2CHRM1CHRM3ACHETAS2R14
SCHEMBL20478039 0.72 IDO1 (0.53) CMA1TAAR1IDO1AGXTCA2
Ammonia Solution, Strong SCHEMBL28351570 0.71 IDO1 (0.51) CMA1TAAR1IDO1AGXTCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321469-B Synthetic method of dibenzyl sulfide 成都理工大学 2022-07-12 CN disclosed