Sugi Predict

Sugi Predict / Compounds / 1-Hydroxy-3-Methoxybenzene

1-Hydroxy-3-Methoxybenzene

1-Hydroxy-3-Methoxybenzene

SCHEMBL7085847

COc1cccc([O-])c1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Al+3]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 2/20 0.49
▸ ACHE P22303 6/20 0.44
▸ GPR3 P46089 2/20 0.40
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ CA12 O43570 1/20 0.39
▸ ABCC9 O60706 1/20 0.39
▸ ABCC8 Q09428 1/20 0.39
▸ KCNJ11 Q14654 1/20 0.39
▸ KCNJ8 Q15842 1/20 0.39
▸ PTGS1 P23219 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ CES2 O00748 1/20 0.39
▸ CES1 P23141 1/20 0.39
▸ ENPP2 Q13822 1/20 0.39
▸ RORA P35398 1/20 0.39
▸ RORC P51449 1/20 0.39
▸ NR1H2 P55055 1/20 0.39
▸ CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Hydroxy-3-Methoxybenzene SCHEMBL7085846 0.89 CES2 (0.41) KCNH2ACHECA1CA2CA9
Trifluoromethanesulfonic Acid SCHEMBL6561809 0.83 ALDH1A1 (0.41) KCNH2ACHEGPR3ALDH1A1
1-Hydroxy-3-Methoxybenzene SCHEMBL8168667 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
1-Hydroxy-3-Methoxybenzene SCHEMBL3289339 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
1-Hydroxy-3-Methoxybenzene SCHEMBL31616066 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
1-Hydroxy-3-Methoxybenzene SCHEMBL3288076 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
1-Hydroxy-3-Methoxybenzene SCHEMBL3287924 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
1-Hydroxy-3-Methoxybenzene SCHEMBL6064728 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
1-Hydroxy-3-Methoxybenzene SCHEMBL6904887 0.78 ACHE (0.54) ACHECA1CA2CA9CES2
Trifluoromethanesulfonic Acid SCHEMBL7089263 0.76 GPR3 (0.44) KCNH2ACHEGPR3CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624321-B2 Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate BAYER AKTIENGESELLSCHAFT (DE) 2003-09-23 — — US disclosed
US-20030097026-A1 Process for the preparation of polyether polyols DENNINGER UWE (DE) 2003-05-22 — — US disclosed
US-6492565-B2 USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST BAYER AKTIENGESELLSCHAFT (DE) 2002-12-10 — — US disclosed
US-20010053866-A1 Process for the preparation of polyether polyols BAYER AKTIENGESELLSCHAFT (DE) 2001-12-20 — — US disclosed
EP-0992524-A2 Process for preparing polyether polyols BAYER AG (DE) 2000-04-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030097026-A1 Process for the preparation of polyether polyols PCBP1, FHIT, PUF60 KCNH2 1955/4885ACHE 4513/4885GPR3 3548/4885
US-20010053866-A1 Process for the preparation of polyether polyols PCBP1, FHIT, PUF60 KCNH2 1955/4885ACHE 4513/4885GPR3 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.