Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720900 | 0.74 | TGFBR1 (0.42) | KMT2ATGFBR1TGFBR2 | |
| SCHEMBL29626235 | 0.72 | PIM1 (0.33) | PIM1TTKPIM2KMT2A | |
| SCHEMBL28838264 | 0.71 | ADRA1D (0.36) | PIM1TTKPIM2KMT2ATGFBR1 | |
| SCHEMBL15680171 | 0.70 | ADRA1D (0.32) | PIM1TTKPIM2KMT2AADRA1D | |
| SCHEMBL29811981 | 0.68 | POLB (0.39) | PIM1TTKPIM2KMT2ATGFBR1 | |
| SCHEMBL19900700 | 0.68 | CYP2C19 (0.46) | PIM1TTKPIM2KMT2A | |
| Hydrochloric Acid SCHEMBL29812382 | 0.66 | ELANE (0.43) | — | |
| SCHEMBL28569830 | 0.66 | MAP2K2 (0.37) | KMT2AKDM4E | |
| SCHEMBL20334824 | 0.66 | ADORA2A (0.32) | — | |
| SCHEMBL29811072 | 0.65 | ELANE (0.43) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627796-B | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |