Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486207 | 0.84 | LMNA (0.54) | POLBLMNARECQLALDH1A1 | |
| SCHEMBL28838264 | 0.83 | ADRA1D (0.36) | POLBLMNARECQLADRA1DL3MBTL1 | |
| SCHEMBL29812644 | 0.77 | MAP2K1 (0.41) | POLBLMNARECQLALDH1A1 | |
| SCHEMBL29626235 | 0.70 | PIM1 (0.33) | POLBL3MBTL1PIM1TTKPIM2 | |
| SCHEMBL19900700 | 0.69 | CYP2C19 (0.46) | ALDH1A1PIM1TTKPIM2KMT2A | |
| SCHEMBL29868051 | 0.69 | TYR (0.44) | ALDH1A1ADRA1D | |
| SCHEMBL29720954 | 0.68 | PIM1 (0.33) | ADRA1DPIM1TTKPIM2KMT2A | |
| SCHEMBL29811977 | 0.67 | IRAK4 (0.35) | ALDH1A1ADRA1DPARP1IRAK4 | |
| SCHEMBL28341822 | 0.66 | CCNC (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29812364 | 0.66 | IRAK4 (0.34) | ADRA1DADRA1APARP1ADRA1BIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787144-A | Pyridone compounds and methods for modulating protein kinases | 埃克塞里艾克西斯公司 | 2022-07-22 | — | — | CN | disclosed |