SCHEMBL297259

SCHEMBL297259

Cl[SiH](Cl)CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TAAR1 Q96RJ0 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
MAOA P21397 4/20 0.42
MAOB P27338 3/20 0.42
CALM1 P0DP23 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
ATM Q13315 1/20 0.41
KEAP1 Q14145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6748579 0.85 ALDH1A1 (0.37) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL523394 0.85 SIGMAR1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL707928 0.83 MAOA (0.52) HTR2AMAOAMAOBSIGMAR1
SCHEMBL1204280 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL20483304 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL19470855 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL19470869 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL20483345 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL19470836 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL19470860 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114130212-B Method for preparing separation membrane by using small molecular monomers 天津工业大学 2025-02-21 CN claimed
CN-114130212-A Method for preparing separation membrane by using small molecule monomer 天津工业大学 2022-03-04 CN claimed
CN-105348513-B A kind of Industrialized synthesis method of cladodification high intensity polysulfone resin 广东优巨先进材料研究有限公司 2017-12-26 CN claimed
WO-2014004146-A1 SILICONE RUBBER EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-01-03 WO claimed
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
JP-2008523165-A 2008-07-03 JP claimed
CN-101098911-A Ultraviolet transmissive polyhedral silsequioxane polymers MATSUSHITA ELECTRIC WORKS LTD (JP) 2008-01-02 CN claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed
US-4309558-A CATALYTIC ALKLATION OR ARALKYLATION CHISSO CORPORATION (JP) 1982-01-05 US claimed
EP-0000614-B1 PRODUCTION OF DICHLOROSILANE DERIVATIVES Chisso Corporation (JP) 1981-11-25 EP claimed
US-4297499-A POLYSILOXANES; SILICONE RUBBERS, OILS, GREASES AND VARNISHES CHISSO CORPORATION (JP) 1981-10-27 US claimed
US-4269993-A Diaralkyldichlorosilanes CHISSO CORPORATION (JP) 1981-05-26 US claimed
US-4242272-A Substituted phenethyldichlorosilanes and method for producing same CHISSO CORPORATION (JP) 1980-12-30 US claimed
US-4228092-A BY ALCOHOL ESTERIFICATION DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-10-14 US claimed
EP-0000614-A1 Production of dichlorosilane derivatives Chisso Corporation (JP) 1979-02-07 EP claimed