Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297259 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL242725 | 0.81 | CALM1 (0.45) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL523394 | 0.73 | SIGMAR1 (0.48) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL707928 | 0.71 | MAOA (0.52) | MAOAMAOBHTR2ACCR3SIGMAR1 | |
| SCHEMBL19470836 | 0.69 | SIGMAR1 (0.52) | MAOAMAOBSIGMAR1 | |
| SCHEMBL19470860 | 0.69 | SIGMAR1 (0.52) | MAOAMAOBSIGMAR1 | |
| SCHEMBL1204280 | 0.69 | SIGMAR1 (0.52) | MAOAMAOBSIGMAR1 | |
| SCHEMBL20483304 | 0.69 | SIGMAR1 (0.52) | MAOAMAOBSIGMAR1 | |
| SCHEMBL20483345 | 0.69 | SIGMAR1 (0.52) | MAOAMAOBSIGMAR1 | |
| SCHEMBL19470869 | 0.69 | SIGMAR1 (0.52) | MAOAMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706398-B1 | FORMING HIGHER HYDROPHOBICITY FILLERS; SURFACE TREATMENT WITH COMBINATION OF MONOMERIC DICHLOROSILANES AND TRIALKOXYSILANES | DOW CORNING CORPORATION | 2004-03-16 | — | — | US | claimed |