Nbi-6024

Nbi-6024

SCHEMBL29355419

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 17/20 0.52
▸ SCTR P47872 1/20 0.52
▸ KEAP1 Q14145 1/20 0.51
▸ TFPI P10646 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556880 0.92 GLP1R (0.57) GLP1RSCTRTFPI
SCHEMBL30262188 0.91 GLP1R (0.59) GLP1RSCTRTFPI
SCHEMBL31211763 0.88 KEAP1 (0.57) GLP1RSCTRKEAP1
SCHEMBL31211842 0.88 KEAP1 (0.57) GLP1RSCTRKEAP1
SCHEMBL30883242 0.88 GLP1R (0.56) GLP1RSCTRTFPI
SCHEMBL30974518 0.87 TFPI (0.62) GLP1RSCTRTFPI
SCHEMBL29822692 0.87 GLP1R (0.59) GLP1RSCTRKEAP1
SCHEMBL29964770 0.87 GLP1R (0.50) GLP1RSCTRKEAP1TFPI
SCHEMBL31307934 0.87 GLP1R (0.56) GLP1RSCTRKEAP1
SCHEMBL31182582 0.86 PTH1R (0.61) GLP1RSCTRKEAP1TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 — — US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 — — US claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 — — EP claimed
WO-2024079739-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — WO claimed
US-20240122847-A1 ORAL POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — US claimed
US-20240122860-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — US claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20260062709-A1 METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN LONZA AG (CH) 2026-03-05 — — US disclosed
US-12534511-B2 Serum albumin-binding fibronectin type III domains BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-27 — — US disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 — — US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 — — US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 — — EP disclosed
CN-114026239-A MUT-methanol nutritional yeast 维也纳自然资源与生命科学大学 2022-02-08 — — CN disclosed
CN-114026213-A Continuous blade type impeller 龙沙有限公司 2022-02-08 — — CN disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 — — US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS GLP1R 319/4885SCTR 126/4885KEAP1 3540/4885
US-12534511-B2 Serum albumin-binding fibronectin type III domains FN1, ALB, FGB GLP1R 4287/4885SCTR 3272/4885KEAP1 4540/4885
US-12533321-B2 Polypeptide formulations for oral delivery PTMS, IAPP, IGF1R GLP1R 4/4885SCTR 343/4885KEAP1 4587/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 GLP1R 116/4885SCTR 169/4885KEAP1 1438/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 GLP1R 139/4885SCTR 668/4885KEAP1 3609/4885
US-20260062709-A1 METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN MRPL21, SET, RPS27A GLP1R 1351/4885SCTR 130/4885KEAP1 3941/4885
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY GLP1R, TTR, IAPP GLP1R 1/4885SCTR 11/4885KEAP1 4825/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT GLP1R 228/4885SCTR 489/4885KEAP1 3528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback