Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340181 | 0.89 | GABRA1 (0.70) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| SCHEMBL12767956 | 0.84 | GABRA1 (0.78) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9812436 | 0.81 | HSD17B10 (0.46) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| SCHEMBL2978694 | 0.79 | GABRA1 (0.52) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9797399 | 0.78 | GABRA1 (0.50) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| SCHEMBL4354075 | 0.75 | IDO1 (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2421445 | 0.74 | TSHR (0.46) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| Methyl Alcohol SCHEMBL28184301 | 0.73 | HSD17B10 (0.88) | GABRA1GABRB1ALDH1A1HSD17B10TSHR | |
| SCHEMBL8872103 | 0.72 | HSD17B10 (1.00) | ALDH1A1HSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL184648 | 0.72 | HSD17B10 (1.00) | ALDH1A1HSD17B10TSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | claimed |
| US-7777073-B2 | Topical delivery system for antiaging and skin whitening agents | BIODERM RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | disclosed |
| US-4282390-A | PARASITICIDES | ICI AUSTRALIA LIMITED (AU) | 1981-08-04 | — | — | US | disclosed |
| US-4163801-A | PARASITICIDES, NEMATOCIDES | ICI AUSTRALIA LIMITED (AU) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | GABRA1 4083/4885GABRB1 3312/4885ALDH1A1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.