Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.48 |
| ▸ | CPN1 | P15169 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281139 | 1.00 | CYP3A4 (0.50) | CYP3A4CASP1RECQLMEN1KMT2A | |
| SCHEMBL30074145 | 1.00 | CYP3A4 (0.50) | CYP3A4CASP1RECQLMEN1KMT2A | |
| SCHEMBL8281143 | 1.00 | CYP3A4 (0.50) | CYP3A4CASP1RECQLMEN1KMT2A | |
| SCHEMBL29687003 | 1.00 | CYP3A4 (0.50) | CYP3A4CASP1RECQLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4983488 | 0.98 | CYP3A4 (0.48) | CYP3A4CASP1RECQLMEN1KMT2A | |
| SCHEMBL2812852 | 0.85 | UGT2B7 (0.56) | CYP3A4MEN1KMT2AUGT2B7ALDH1A1 | |
| SCHEMBL9331659 | 0.85 | UGT2B7 (0.56) | CYP3A4MEN1KMT2AUGT2B7ALDH1A1 | |
| SCHEMBL9331663 | 0.85 | UGT2B7 (0.56) | CYP3A4MEN1KMT2AUGT2B7ALDH1A1 | |
| SCHEMBL9334664 | 0.85 | UGT2B7 (0.56) | CYP3A4MEN1KMT2AUGT2B7ALDH1A1 | |
| SCHEMBL272384 | 0.83 | CYP3A4 (0.52) | CYP3A4CASP1RECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | claimed |
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | claimed |
| CN-118451062-A | Preparation and use of quinazolinediones | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-06 | — | — | CN | claimed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | claimed |
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | claimed |
| EP-4171569-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2023-05-03 | — | — | EP | claimed |
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | claimed |
| CN-104531397-A | Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof | HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-101907835-B | Detergent composition for photoresists | ANJI MICROELECTRONICS SHANGHAI | 2013-08-28 | — | — | CN | claimed |
| CN-101614971-B | Photoresist cleaning agent | ANJI MICROELECTRONICS CO LTD | 2013-06-12 | — | — | CN | claimed |
| US-20040072952-A1 | Reactive hot melt adhesive with non-polymeric aromatic difunctionals | HENKEL AG & CO. KGAA (DE) | 2004-04-15 | — | — | US | claimed |
| WO-2003093352-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | claimed |
| EP-1361245-A1 | Amino-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-12 | — | — | EP | claimed |
| US-6417249-B1 | INK JET PRINTING INK FOR COLOR VEHICLES, CORE/SHELL BINDERS, SMUDGE PROOF | HEWLETT-PACKARD COMPANY | 2002-07-09 | — | — | US | claimed |
| US-6372030-B1 | INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID | XEROX CORPORATION | 2002-04-16 | — | — | US | claimed |
| EP-1035179-A1 | Ink-jet printing ink compositions having superior smear-fastness | Hewlett-Packard Company (US) | 2000-09-13 | — | — | EP | claimed |
| EP-1027393-A1 | PRINTING INK COMPOSITIONS HAVING SUPERIOR SMEAR-FASTNESS | Hewlett-Packard Company (US) | 2000-08-16 | — | — | EP | claimed |
| WO-1999023183-A1 | PRINTING INK COMPOSITIONS HAVING SUPERIOR SMEAR-FASTNESS | HEWLETT-PACKARD COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| US-4024187-A | Preparation of m-amino-α-methylbenzyl alcohol | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1977-05-17 | — | — | US | claimed |
| US-4021487-A | Preparation of m-amino-α-methylbenzyl alcohol | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1977-05-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | CYP3A4 433/4885CASP1 1993/4885RECQL 788/4885 |
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | ATG7, GOT1, ULK1 | CYP3A4 947/4885CASP1 2340/4885RECQL 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.