SCHEMBL2974508

SCHEMBL2974508

CC(C)c1ccc(N)cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
SLC6A2 P23975 2/20 0.59
HTR2B P41595 2/20 0.59
TRPA1 O75762 1/20 0.59
CHRM1 P11229 1/20 0.59
ADRA1A P35348 1/20 0.59
TSHR P16473 2/20 0.52
CASP1 P29466 1/20 0.52
GABRA1 P14867 3/20 0.48
GABRB2 P47870 3/20 0.48
PDE10A Q9Y233 1/20 0.46
GAA P10253 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP3A4 P08684 2/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31240541 1.00 LMNA (0.59) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL6152512 0.84 CASP1 (0.50) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL29260566 0.84 TSHR (0.50) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL2739345 0.82 PDE10A (0.52) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL2379856 0.78 ANPEP (0.41) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL30102587 0.78 ANPEP (0.41) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL5486247 0.76 CASP1 (0.48) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL383417 0.76 LMNA (0.64) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL16528005 0.76 LMNA (0.64) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL29368425 0.76 CASP1 (0.48) LMNASLC6A2HTR2BTRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3758083-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2025-05-28 EP disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 US disclosed
US-11605788-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-14 US disclosed
US-20200411764-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-31 US disclosed
US-20200411764-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-31 US disclosed
EP-3758083-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2020-12-30 EP disclosed
CN-112151684-A Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2020-12-29 CN disclosed
EP-2382197-B1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2016-10-05 EP disclosed
US-9034254-B2 Titanium oxide immobilized with bioreceptors and antibacterial method using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-05-19 US disclosed
US-9018209-B2 Compounds and methods for the treatment of viruses and cancer YALE UNIVERSITY (US) 2015-04-28 US disclosed
US-7989430-B2 Antibacterial agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-08-02 US disclosed
US-20100222352-A1 Compounds and Methods for the Treatment of Viruses and Cancer YALE UNIVERSITY (US) 2010-09-02 US disclosed
US-20100184739-A1 Modulators of ATP-Binding Cassette Transporters VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-22 US disclosed
US-20100184739-A1 Modulators of ATP-Binding Cassette Transporters VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-22 US disclosed
US-20100184739-A1 Modulators of ATP-Binding Cassette Transporters VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-22 US disclosed
WO-2010078103-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-08 WO disclosed
US-20100168094-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-01 US disclosed
US-20100168094-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-07-01 US disclosed
US-20080293666-A1 Antibacterial Agents REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2008-11-27 US disclosed
WO-2007038387-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER YALE UNIVERSITY (US) 2007-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184739-A1 Modulators of ATP-Binding Cassette Transporters CFTR, ABCB1, ABCC2 LMNA 2816/4885SLC6A2 431/4885HTR2B 3414/4885
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R LMNA 3279/4885SLC6A2 1205/4885HTR2B 2669/4885
US-20100222352-A1 Compounds and Methods for the Treatment of Viruses and Cancer RCOR1, RCOR3, CCNT1 LMNA 3951/4885SLC6A2 3973/4885HTR2B 3264/4885
US-20100168094-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, ABCB1, ABCC2 LMNA 3871/4885SLC6A2 1488/4885HTR2B 3640/4885
US-20080293666-A1 Antibacterial Agents MRPL21, ABCB7, MSR1 LMNA 2265/4885SLC6A2 1931/4885HTR2B 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.