Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAD | P27708 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 7/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051973 | 0.84 | GRN (0.39) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL29750216 | 0.82 | GRN (0.54) | CADGRNSORT1MAPK1POLB | |
| SCHEMBL30030351 | 0.82 | CTSS (0.37) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL23051872 | 0.81 | CTSK (0.38) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL23051981 | 0.81 | GRN (0.40) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL20571233 | 0.80 | GRN (0.40) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL20571234 | 0.80 | GRN (0.40) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL27513177 | 0.79 | NPSR1 (0.51) | MAPK1TDP1POLBNPSR1CTSK | |
| SCHEMBL22262968 | 0.79 | MAPK1 (0.38) | GRNSORT1MAPK1TDP1POLB | |
| SCHEMBL13993198 | 0.79 | GRN (0.43) | GRNSORT1MAPK1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794422-B | Heterocyclic compounds as PD-L1 inhibitors | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |