Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.64 |
| ▸ | ELANE | P08246 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | CCR2 | P41597 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447718 | 0.84 | LMNA (0.74) | ALDH1A1GAAHSD17B10LMNARAB9A | |
| SCHEMBL23447721 | 0.83 | MLYCD (0.77) | ALDH1A1GAALMNARAB9AMEN1 | |
| SCHEMBL13876855 | 0.82 | HDAC1 (0.62) | ELANEEPHX2 | |
| SCHEMBL3238166 | 0.82 | MLYCD (0.61) | ALDH1A1GAALMNARAB9AMAPT | |
| SCHEMBL933464 | 0.81 | ALDH1A1 (0.72) | ALDH1A1GAAHSD17B10EPHX2NR1H4 | |
| SCHEMBL11626087 | 0.81 | VNN1 (0.63) | ALDH1A1GAALMNARAB9AMEN1 | |
| SCHEMBL11715172 | 0.79 | LMNA (0.71) | LMNARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6193328 | 0.78 | NR1H4 (0.57) | ALDH1A1GAAHSD17B10EPHX2NR1H4 | |
| SCHEMBL561061 | 0.78 | ELANE (1.00) | ELANE | |
| SCHEMBL15647658 | 0.78 | NAMPT (0.62) | DDR1ELANELMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436955-A | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2022-05-06 | — | — | CN | disclosed |