SCHEMBL29754547

SCHEMBL29754547

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.55
▸ GHSR Q92847 4/20 0.51
▸ PRKACB P22694 1/20 0.50
▸ TUBB4A P04350 1/20 0.49
▸ TUBB P07437 1/20 0.49
▸ TUBA3C P0DPH7 1/20 0.49
▸ TUBA1B P68363 1/20 0.49
▸ TUBA4A P68366 1/20 0.49
▸ TUBB4B P68371 1/20 0.49
▸ TUBB3 Q13509 1/20 0.49
▸ TUBB2A Q13885 1/20 0.49
▸ TUBB8 Q3ZCM7 1/20 0.49
▸ TUBA3E Q6PEY2 1/20 0.49
▸ TUBA1A Q71U36 1/20 0.49
▸ TUBA1C Q9BQE3 1/20 0.49
▸ TUBB6 Q9BUF5 1/20 0.49
▸ TUBB2B Q9BVA1 1/20 0.49
▸ TUBB1 Q9H4B7 1/20 0.49
▸ NMBR P28336 1/20 0.47
▸ CTSL P07711 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29461990 0.97 C5AR1 (0.54) C5AR1GHSRPRKACBTUBB4ATUBB
SCHEMBL29484172 0.95 C5AR1 (0.59) C5AR1GHSRPRKACBTUBB4ATUBB
SCHEMBL30130567 0.95 C5AR1 (0.61) C5AR1GHSRPRKACBTUBB4ATUBB
SCHEMBL30130535 0.95 C5AR1 (0.61) C5AR1GHSRPRKACBTUBB4ATUBB
SCHEMBL30093087 0.94 C5AR1 (0.60) C5AR1GHSRPRKACBTUBB4ATUBB
SCHEMBL30878115 0.94 GHSR (0.57) C5AR1GHSRTUBB4ATUBBTUBA3C
SCHEMBL31091318 0.94 C5AR1 (0.48) C5AR1CTSLCTSHCTSSCTSK
SCHEMBL29754637 0.94 CTSL (0.52) C5AR1GHSRPRKACBTUBB4ATUBB
SCHEMBL31680253 0.93 C5AR1 (0.61) C5AR1GHSRTUBB4ATUBBTUBA3C
SCHEMBL31473233 0.93 NPBWR1 (0.53) C5AR1GHSRPRKACBTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094324-B Oncolytic virus, synthetic DNA sequence and application thereof 武汉博威德生物技术有限公司 2023-10-10 — — CN claimed
US-20220288142-A1 RECOMBINANT ONCOLYTIC VIRUS, SYNTHETIC DNA SEQUENCE, AND APPLICATION THEREOF Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-09-15 — — US claimed
CN-111094324-B Oncolytic virus, synthetic DNA sequence and application thereof 武汉博威德生物技术有限公司 2023-10-10 — — CN disclosed
US-20220288142-A1 RECOMBINANT ONCOLYTIC VIRUS, SYNTHETIC DNA SEQUENCE, AND APPLICATION THEREOF Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-09-15 — — US disclosed
US-11376290-B2 Recombinant oncolytic virus, synthetic DNA sequence, and application thereof Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-07-05 — — US disclosed
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