Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754547 | 0.97 | C5AR1 (0.55) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL30974091 | 0.94 | C5AR1 (0.57) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL31732172 | 0.93 | CTSL (0.51) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL30974212 | 0.93 | C5AR1 (0.56) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29484172 | 0.92 | C5AR1 (0.59) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29540499 | 0.92 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29641153 | 0.92 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29884974 | 0.92 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29461998 | 0.92 | C5AR1 (0.58) | C5AR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30130567 | 0.92 | C5AR1 (0.61) | C5AR1PRKACBTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250262269-A1 | METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE | STEALTH BIOTHERAPEUTICS INC. (US) | 2025-08-21 | — | — | US | disclosed |
| US-20240024408-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-01-25 | — | — | US | disclosed |
| US-20230346874-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230212220-A1 | METHODS FOR REDUCING CD36 EXPRESSION | CORNELL RESEARCH FOUNDATION, INC. (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230201299-A1 | METHODS FOR THE PREVENTION AND TREATMENT OF BURN INJURIES AND SECONDARY COMPLICATIONS | THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL (US) | 2023-06-29 | — | — | US | disclosed |
| US-20230076067-A1 | MITOCHONDRIAL-TARGETED ANTIOXIDANTS PROTECT AGAINST MECHANICAL VENTILATION-INDUCED DIAPHRAGM DYSFUNCTION AND SKELETAL MUSCLE ATROPHY | CORNELL UNIVERSITY (US) | 2023-03-09 | — | — | US | disclosed |
| US-11534476-B2 | Methods for the prevention or treatment of heart failure | CORNELL UNIVERSITY (US) | 2022-12-27 | — | — | US | disclosed |
| US-20220296671-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-09-22 | — | — | US | disclosed |
| US-11447523-B2 | Methods for reducing CD36 expression | CORNELL RESEARCH FOUNDATION, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20220280593-A1 | METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-09-08 | — | — | US | disclosed |
| US-11266709-B2 | Methods for the regulation of matrix metalloproteinase expression | STEALTH BIOTHERAPEUTICS INC. (US) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230076067-A1 | MITOCHONDRIAL-TARGETED ANTIOXIDANTS PROTECT AGAINST MECHANICAL VENTILATION-INDUCED DIAPHRAGM DYSFUNCTION AND SKELETAL MUSCLE ATROPHY | HSPA9, OPA1, ARG2 | C5AR1 1852/4885CTSL 1232/4885CTSS 1091/4885 |
| US-20240024408-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING LEBER'S HEREDITARY OPTIC NEUROPATHY | CLN6, PRPH, TSG101 | C5AR1 964/4885CTSL 2433/4885CTSS 1526/4885 |
| US-11534476-B2 | Methods for the prevention or treatment of heart failure | TNNI3, FABP3, TNNC1 | C5AR1 1061/4885CTSL 860/4885CTSS 1235/4885 |
| US-20230201299-A1 | METHODS FOR THE PREVENTION AND TREATMENT OF BURN INJURIES AND SECONDARY COMPLICATIONS | MUSK, TNNC1, TNNI3 | C5AR1 265/4885CTSL 111/4885CTSS 273/4885 |
| US-20220280593-A1 | METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE | RNPEP, TNNI3, BDKRB1 | C5AR1 104/4885CTSL 384/4885CTSS 269/4885 |
| US-20230346874-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS | CRYAA, CRYAB, IAPP | C5AR1 264/4885CTSL 1699/4885CTSS 1029/4885 |
| US-20220296671-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING | ARG2, TNNT2, MYLK2 | C5AR1 3385/4885CTSL 830/4885CTSS 1864/4885 |
| US-20250262269-A1 | METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE | RNPEP, TNNI3, BDKRB1 | C5AR1 104/4885CTSL 384/4885CTSS 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.