SCHEMBL29754637

SCHEMBL29754637

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 3/20 0.52
▸ CTSS P25774 3/20 0.52
▸ CTSK P43235 3/20 0.52
▸ CTSH P09668 1/20 0.52
▸ C5AR1 P21730 2/20 0.52
▸ GHSR Q92847 8/20 0.48
▸ PRKACB P22694 1/20 0.48
▸ IL23R Q5VWK5 1/20 0.47
▸ TUBB4A P04350 1/20 0.47
▸ TUBB P07437 1/20 0.47
▸ TUBA3C P0DPH7 1/20 0.47
▸ TUBA1B P68363 1/20 0.47
▸ TUBA4A P68366 1/20 0.47
▸ TUBB4B P68371 1/20 0.47
▸ TUBB3 Q13509 1/20 0.47
▸ TUBB2A Q13885 1/20 0.47
▸ TUBB8 Q3ZCM7 1/20 0.47
▸ TUBA3E Q6PEY2 1/20 0.47
▸ TUBA1A Q71U36 1/20 0.47
▸ TUBA1C Q9BQE3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30636163 0.97 CTSL (0.52) CTSLCTSSCTSKCTSHC5AR1
SCHEMBL29754547 0.94 C5AR1 (0.55) CTSLCTSSCTSKCTSHC5AR1
SCHEMBL31232428 0.92 GHSR (0.52) GHSRPRKACBIL23RNPY2RCTSC
SCHEMBL29461990 0.91 C5AR1 (0.54) CTSLCTSSCTSKCTSHC5AR1
SCHEMBL31091318 0.90 C5AR1 (0.48) CTSLCTSSCTSKCTSHC5AR1
SCHEMBL30130567 0.90 C5AR1 (0.61) C5AR1GHSRPRKACBIL23RTUBB4A
SCHEMBL30130535 0.90 C5AR1 (0.61) C5AR1GHSRPRKACBIL23RTUBB4A
SCHEMBL30138626 0.90 C5AR1 (0.54) CTSLCTSSCTSKCTSHC5AR1
SCHEMBL30550555 0.90 TUBB4A (0.55) CTSLCTSSCTSKCTSHC5AR1
SCHEMBL31680253 0.89 C5AR1 (0.61) C5AR1GHSRTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094324-B Oncolytic virus, synthetic DNA sequence and application thereof 武汉博威德生物技术有限公司 2023-10-10 — — CN claimed
US-20220288142-A1 RECOMBINANT ONCOLYTIC VIRUS, SYNTHETIC DNA SEQUENCE, AND APPLICATION THEREOF Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-09-15 — — US claimed
US-11376290-B2 Recombinant oncolytic virus, synthetic DNA sequence, and application thereof Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-07-05 — — US claimed
CN-111094324-B Oncolytic virus, synthetic DNA sequence and application thereof 武汉博威德生物技术有限公司 2023-10-10 — — CN disclosed
US-20220288142-A1 RECOMBINANT ONCOLYTIC VIRUS, SYNTHETIC DNA SEQUENCE, AND APPLICATION THEREOF Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-09-15 — — US disclosed
US-11376290-B2 Recombinant oncolytic virus, synthetic DNA sequence, and application thereof Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-07-05 — — US disclosed
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