SCHEMBL29757447

SCHEMBL29757447

Cn1nnc(-c2ccc(N)c(C(F)F)n2)c1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAP2K3 P46734 1/20 0.31
ADCY10 Q96PN6 1/20 0.30
HCAR3 P49019 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757476 0.87 ADCY10 (0.35) ADCY10
SCHEMBL23363247 0.87 ADCY10 (0.35) ADCY10
SCHEMBL31345080 0.85 LPAR1 (0.32) HCAR3
SCHEMBL30862887 0.82
SCHEMBL23362854 0.79 PTGES (0.33)
SCHEMBL29757438 0.79 PTGES (0.33)
SCHEMBL29757478 0.72 ALDH1A1 (0.32) ADCY10
SCHEMBL23363685 0.72 ALDH1A1 (0.32) ADCY10
SCHEMBL25224521 0.72 LDHA (0.35) ADCY10HCAR3
SCHEMBL31345056 0.71 ALDH1A1 (0.34) HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728168-A Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use 吉利德科学公司 2022-07-08 CN disclosed