Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25881 | 0.87 | ESR1 (0.58) | TYRESR1ESR2CYP3A4TSHR | |
| SCHEMBL4348947 | 0.82 | ESR1 (0.67) | CA2CA1CA12CA3TYR | |
| Bisphenol A SCHEMBL2854094 | 0.82 | ESR1 (0.67) | CA2CA1CA12CA3TYR | |
| Bisphenol A SCHEMBL11427584 | 0.80 | ESR1 (0.64) | CA2CA1CA12CA3TYR | |
| Terephthalic Acid SCHEMBL29759542 | 0.80 | CA2 (0.50) | CA2CA1CA12CA3TYR | |
| Bisphenol A SCHEMBL5935233 | 0.75 | ESR1 (0.70) | CA2CA1CA12CA3TYR | |
| Bisphenol A SCHEMBL1683933 | 0.74 | ESR1 (0.55) | CA2CA1CA12CA3TYR | |
| Bisphenol A SCHEMBL6933678 | 0.74 | ESR1 (0.55) | CA2CA1CA12CA3TYR | |
| SCHEMBL1635858 | 0.74 | SRD5A2 (0.65) | CA2CA1CA12CA3TYR | |
| SCHEMBL71433 | 0.74 | SRD5A2 (0.65) | CA2CA1CA12CA3TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404437-B2 | Fiber reinforced flexible foams | L&P PROPERTY MANAGEMENT COMPANY (US) | 2025-09-02 | — | — | US | disclosed |
| US-20220259478-A1 | Fiber Reinforced Flexible Foams | L&P PROPERTY MANAGEMENT COMPANY | 2022-08-18 | — | — | US | disclosed |
| US-11401451-B2 | Fiber reinforced flexible foams | L&P PROPERTY MANAGEMENT COMPANY (US) | 2022-08-02 | — | — | US | disclosed |