SCHEMBL297618

SCHEMBL297618

Nc1ccc(C(=O)NO)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61
PKM P14618 1/20 0.61
APEX1 P27695 1/20 0.61
KMT2A Q03164 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
HDAC6 Q9UBN7 8/20 0.60
HDAC1 Q13547 7/20 0.60
HDAC2 Q92769 3/20 0.60
HDAC8 Q9BY41 3/20 0.60
HDAC3 O15379 2/20 0.59
NCOR2 Q9Y618 2/20 0.59
CA1 P00915 2/20 0.58
CA12 O43570 1/20 0.58
IDO1 P14902 1/20 0.58
ALOX15 P16050 1/20 0.58
CA9 Q16790 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HSD17B10 Q99714 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3673435 0.87 HDAC6 (0.75) HDAC6HDAC1HDAC2HDAC8HDAC3
SCHEMBL28624169 0.86 MAPT (0.70) MEN1LMNAPOLBPKMAPEX1
SCHEMBL23918991 0.82 LMNA (0.64) MEN1LMNAPOLBPKMAPEX1
SCHEMBL9921348 0.82 POLB (0.64) MEN1LMNAPOLBPKMAPEX1
SCHEMBL2640636 0.80 HDAC6 (0.60) POLBKMT2ATDP1HDAC6HDAC1
SCHEMBL328628 0.80 HIF1A (0.67) MEN1LMNAPOLBPKMAPEX1
SCHEMBL12687823 0.80 OGG1 (0.71) LMNAHDAC6HDAC1HDAC2HDAC8
SCHEMBL25060935 0.79 HDAC1 (0.75) HDAC6HDAC1HDAC2HDAC8HDAC3
SCHEMBL158878 0.78 HDAC2 (0.64) MEN1LMNAPOLBPKMAPEX1
SCHEMBL16336479 0.78 LMNA (0.59) MEN1LMNAPOLBPKMAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240319601-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2024-09-26 US claimed
CN-117597628-A Method for forming pattern 三星SDI株式会社 2024-02-23 CN claimed
US-20240019784-A1 METAL CONTAINING PHOTORESIST DEVELOPER COMPOSITION, AND METHOD OF FORMING PATTERNS INCLUDING STEP OF DEVELOPING USING THE COMPOSITION SAMSUNG SDI CO., LTD. (KR) 2024-01-18 US claimed
CN-117348341-A Metal-containing photoresist developer composition and pattern forming method 三星SDI株式会社 2024-01-05 CN claimed
WO-2023003215-A1 METHOD OF FORMING PATTERNS 삼성에스디아이 주식회사 2023-01-26 WO claimed
US-10040682-B2 Functionally switchable self-assembled coating compound for controlling translocation of molecule through nanopores INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-08-07 US claimed
US-10029915-B2 Functionally switchable self-assembled coating compound for controlling translocation of molecule through nanopores INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-07-24 US claimed
US-9115090-B2 Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2015-08-25 US claimed
US-20130263946-A1 FUNCTIONALLY SWITCHABLE SELF-ASSEMBLED COATING COMPOUND FOR CONTROLLING TRANSLOCATION OF MOLECULE THROUGH NANOPORES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-10 US claimed
US-20130264219-A1 FUNCTIONALLY SWITCHABLE SELF-ASSEMBLED COATING COMPOUND FOR CONTROLLING TRANSLOCATION OF MOLECULE THROUGH NANOPORES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-10 US claimed
US-8492293-B1 High density selective deposition of carbon nanotubes onto a substrate INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-07-23 US claimed
US-8394727-B1 High density selective deposition of carbon nanotubes onto a substrate INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-03-12 US claimed
US-20070225373-A1 Zn2Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2007-09-27 US claimed
EP-1696898-A2 ZN 24 -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2006-09-06 EP claimed
WO-2005055928-A2 ZN2+ -CHELATING MOTIF-TETHERED SHORT -CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2005-06-23 WO claimed
EP-1461010-A2 HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS Integriderm, Inc. (US) 2004-09-29 EP claimed
US-20030199558-A1 Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners INTEGRIDERM, INC. 2003-10-23 US claimed
WO-2003057184-A2 HYDROXAMIC ACID AND ITS DERIVATIVES AS INHIBITORS OF MELANOCYTE TYROSINASE FOR TOPICAL SKIN LIGHTENERS INTEGRIDERM, INC. (US) 2003-07-17 WO claimed
US-20240319601-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2024-09-26 US disclosed
US-4394389-A ANTITUMOR AGENTS RIET BARTHOLOMEUS VAN T 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199558-A1 Hydroxamic acid and its derivatives as inhibitors of melanocyte tyrosinase for topical skin lighteners TYR, MC1R, MITF MEN1 2507/4885LMNA 2177/4885POLB 1199/4885
US-20070225373-A1 Zn2Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase HDAC1, BAZ2B, HDAC11 MEN1 4539/4885LMNA 2545/4885POLB 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.