SCHEMBL29763757

SCHEMBL29763757

O=C(O)c1ccc(C(=O)OCC2CO2)c(C(=O)O)c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.44
MGLL Q99685 6/20 0.43
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2779445 0.87 DHFR (0.48) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL9105345 0.85 DHFR (0.41) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL529997 0.83 DHFR (0.54) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL21801769 0.83 DHFR (0.54) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL30541879 0.83 DHFR (0.54) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL19732909 0.82 DHFR (0.49) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL27669934 0.82 DHFR (0.49) DHFRMGLLMAPK1L3MBTL1
SCHEMBL1373567 0.82 DHFR (0.49) DHFRMGLL
SCHEMBL7179948 0.82 DHFR (0.44) DHFRMGLLMAPK1L3MBTL1ALDH1A1
SCHEMBL31651033 0.82 DHFR (0.44) DHFRMGLLMAPK1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022168892-A1 POLYMERIZABLE COMPOSITION, RESIN, MOLDED ARTICLE, OPTICAL MATERIAL, AND LENS 三井化学株式会社 2022-08-11 WO disclosed