Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726452 | 1.00 | CA2 (0.47) | CA2CA1CA9PKMRAB9A | |
| SCHEMBL2964374 | 0.84 | CHEK1 (0.39) | CA2CA1CA9CHEK1NEK2 | |
| SCHEMBL2679932 | 0.83 | CYP2D6 (0.43) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL1660887 | 0.83 | PAX8 (0.41) | CA2CA1CA9CHEK1NEK2 | |
| SCHEMBL29827543 | 0.83 | PAX8 (0.41) | CA2CA1CA9CHEK1NEK2 | |
| SCHEMBL5608087 | 0.83 | SIGMAR1 (0.40) | CA2CA1CA9RAB9ACHEK1 | |
| SCHEMBL30502409 | 0.83 | CYP2D6 (0.43) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL7595952 | 0.82 | CHEK1 (0.39) | CA2CA1CA9CHEK1NEK2 | |
| Hydrochloric Acid SCHEMBL28101819 | 0.81 | EP300 (0.43) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL7298973 | 0.79 | G6PD (0.37) | CA2CHEK1NEK2LIMK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558479-A1 | NOVEL NAPHTHYL AND ISOQUINOLINE SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024017858-A1 | NOVEL NAPHTHYL AND ISOQUINOLINE SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-25 | — | — | WO | disclosed |
| CN-108760950-B | Method for determining nitrofuran metabolite | 国检测试控股集团京诚检测有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-108760950-B | Method for determining nitrofuran metabolite | 国检测试控股集团京诚检测有限公司 | 2022-07-15 | — | — | CN | disclosed |