Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cresol SCHEMBL9478964 | 0.86 | ACHE (0.62) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| P-Cresol SCHEMBL11600098 | 0.86 | ACHE (0.68) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| Nonane SCHEMBL27776640 | 0.84 | ACHE (0.65) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| Dodecane SCHEMBL28591401 | 0.84 | ACHE (0.65) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| Octane SCHEMBL11602147 | 0.84 | ACHE (0.65) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| P-Xylene SCHEMBL28101427 | 0.81 | DNM1 (0.60) | ACHEALDH1A1TAAR1L3MBTL1CYP1A2 | |
| P-Cresol SCHEMBL6767262 | 0.81 | ACHE (0.77) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| Phenol SCHEMBL4630205 | 0.80 | CA12 (0.50) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| Phenol SCHEMBL28038383 | 0.80 | CA12 (0.50) | ACHEESR1ADRA2ASLC6A2KDM4E | |
| P-Cresol SCHEMBL168366 | 0.80 | ACHE (0.59) | ACHEESR1ADRA2ASLC6A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12366579-B2 | Sulfur-heterocycle exchange chemistry and uses thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-07-22 | — | — | US | disclosed |
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220214355-A1 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | TST, TPST2, SRMS | ACHE 3899/4885ESR1 3331/4885ADRA2A 4850/4885 |
| US-12366579-B2 | Sulfur-heterocycle exchange chemistry and uses thereof | TST, TPST2, SRMS | ACHE 3899/4885ESR1 3331/4885ADRA2A 4850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.