Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.43 |
| ▸ | RBP4 | P02753 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726937 | 0.81 | TRPM8 (0.58) | ALDH1A1LMNATRPM8HTTSGMS2 | |
| SCHEMBL24627541 | 0.81 | EGFR (0.49) | ALDH1A1TDP1 | |
| SCHEMBL10102481 | 0.80 | HRH1 (0.40) | ALDH1A1KDM4ERBP4HRH1L3MBTL1 | |
| SCHEMBL24627820 | 0.80 | L3MBTL1 (0.58) | LMNATRPM8HTTSGMS2MAPK1 | |
| SCHEMBL524847 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EHRH1TSHRMAPK1 | |
| SCHEMBL7367495 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1TDP1L3MBTL1 | |
| SCHEMBL29777975 | 0.78 | KMT2A (0.55) | — | |
| SCHEMBL24627426 | 0.78 | KMT2A (0.55) | — | |
| SCHEMBL10102483 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4ERBP4HRH1L3MBTL1 | |
| SCHEMBL19384151 | 0.78 | HRH1 (0.46) | ALDH1A1KDM4ELMNAHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148879-A1 | QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF ACKR3 | STICHTING VU (NL) | 2022-07-14 | — | — | WO | disclosed |